goodduck

Keypoint: chronic inflammation involving genetic defect!

Clinical Manifestation

1. course: 60%(1歲前)->85%(5歲前)

2. dry skin!

infantile(0~2y/o)

特徵: pruritic, red, scaly, and crusted ; 在acute stage可見vesicle或crust

分佈: extensor surface / cheek / scalp ; 包尿布的地方通常不會有!!!

child(2~12y/o)

chronic inflammation->已經可見lichenified plaqge 

分佈: 在四肢flexion處(特別是antecubital/popliteal fossa) ; ie: 四彎風

adult(>12 y/o)

與child類似但更明顯的plague: skin thickening, lichenified, fibrotic plague;

分佈: 與child相同, 也是在flexural areas (neck, antecubital fossae, and popliteal fossae),其它常見的地方為 face, wrists, and forearms

# 分佈在axilla / gluteal / groin不常見,先考慮psoriasis